Effect of injection of vitamin C and copper to transition dairy cows on colostrum composition and serum metabolites of neonatal calves

Document Type : Research Paper

Authors

1 PhD student, Department of Animal Science, Ilam University, Ilam, Iran.

2 Scientific member of Animal Science Department in Ilam University

3 Animal Science Research Department, Ilam Agricultural and Natural Resources Research and Education Center, AREEO, Ilam, Iran.

4 Department of Animal science, Faculty of Agriculture, Ilam University

Abstract

In the present study the effect of vitamin C and copper injection in transition dairy cows on colostrum composition and serum metabolites of neonatal dairy calves was examined. Twenty multiparous (second parity, with 603.2 ± 53 kg average BW) and twenty multiparous (third and fourth parity, 669.1± 51 kg average BW) selected and divided to four balanced groups based on BW abd parity. Experimental treatments consisted of control (injection of 7 ml of NaCl % 0.9), Vitamin C (injection of 25 mg vitamin C solution/kg BW), Copper (injection of 75 mg copper solution/day) and Vitamin C-Copper (simultaneous injection of 25 mg vitamin C solution/ kg BW and 75 mg copper solution/day). Solutions were injected on d 20 and 40 before of expected calving. Copper injection increased red blood cells counts and serum concentration of copper (P < 0.05) compared with not injected groups. Colostrum fat, protein, lactose, solid not fat and immunoglobulin G concentrations, calf birth weight, serum concentration of vitamin C, superoxide dismutase, calcium, phosphorus and metabolites did not affected by simultaneous injections of vitamin C and copper solutions. Blood neutrophil count in calves of cows receiving simultaneous injection of vitamin C and copper solutions tended to increase (P = 0.06) compared with other groups. In general, simultaneous injection of vitamin C and copper during the dry period had no effect on colostrum composition and blood parameters in postpartum dairy cows, but may improve immunity system of their calves by increasing blood neutrophil concentration.

Keywords

References

چراغی‌مشعوف، ل. (1395). اثرات مکمل­های روی و مس بر برخی فراسنجه­های خون و عملکرد میش­های آبستن و بره­های آن‌ها. پایان نامه کارشناسی ارشد. دانشگاه بوعلی سینا همدان.
Association of Official Analytical Chemists .(2007). Official methods of analysis. 18th Edition. AOAC, Gaithersburg, MD, USA.
Ashraf Hesari, B., Mohri, M. and Seifi, H.A. (2012). Effect of copper edetate injection in dry pregnant cows on hematology, blood metabolites, weight gain and health of calves. Tropical Animal Health and Production. 44:1041–1047.
Bicalho, M.L., Lima, F.S., Ganda, E.K., Foditsch, C., Meira, E.B.J., Machado, V.S. et al. (2014) Effect of trace mineral supplementation on selected minerals, energy metabolites, oxidative  stress, and immune parameters and its association with uterine diseases in dairy cattle. Journal of Dairy Science. 97:1–15.
Erb, C., Staudt, N., Flammer, J. and Nau, W. (2004). Ascorbic acid as a free radical scavenger in porcine and bovine aqueous humour. Ophtalmic Research. 36:38-42.
Esposito, G., Irons, P.C., Webb, E.C. and Chapwanya, A. (2014). Interactions between negative energy balance, metabolic diseases, uterine health and immune response in transition dairy cows. Animal Reproduction Science. 144:60-71.
Ganda, E.K., Bisinotto, R.S., Vasquez, A.K., Teixeira, A.G.V., Machado, VS., Foditsch, C. et al. (2016). Effects of injectable trace mineral supplementation in lactating dairy cows with elevated somatic cell counts. Journal of Dairy Science. 99:7319–7329.
Gengelbach, G.P., Ward, J.D. and Spears, J.W. (1994). Effect of dietary copper, iron and molybdenum on growth and copper status of beef cows and calves. Journal of Animal Science. 72:2722- 2727.
Godden, S. (2008). Colostrum management for dairy calves. Veterinary Clinics of Food Animal Practice. 24:19–39.
Grummer, R.R. (1995). Impact of changes in organic nutrient metabolism on feeding the transition dairy cow. Journal of Animal Science. 73:2820-2833.
Hasslet, C., Savill, S. and Meagher, L. (1998). The neutrophil. Current Opinion in Immunology. 88:96-98.
Hattangadi, S.M. and Lodish, H.F. (2007). Regulation of erythrocyte lifespan: do reactive oxygen species set the clock? The Journal of Clinical Investigation. 117:2075–2077.
Inemani, O., Shiga, A., Okada, K., Sato, R., Miyake, Y. I. and Kuwabara, M.  (1999).  Lipid peroxides and antioxidants in serum of neonatal calves. Journal of Veterinary Research 60:452-457.
Karkoodi, K., Chamani, M., Beheshti, M., Mirghaffari, S.S. and Azarfar, A. (2012). Effect of Organic zinc, manganese, copper, and selenium chelates on colostrum production and reproductive and lameness indices in adequately supplemented Holstein cows. Biological Trace Element Research. 146:42–46.
Machado, V.S., Oikonomou, G., Lima, S.F., Bicalhoa, M.L., Kacar, C., Foditsch, C. et al. (2014). The effect of injectable trace minerals (selenium, copper, zinc, and manganese) on peripheral blood leukocyte activity and serum superoxide dismutase activity of lactating Holstein cows. Veterinary Journal. 200:299–304.
Marques, R.S., Cooke, R.F., Rodrigues, M.C., Cappellozza, B.I., Mills, R.R., Larson, C.K. et al. (2016). Effects of organic or inorganic cobalt, copper, manganese, and zinc supplementation to late-gestating beef cows on productive and physiological responses of the offspring. Journal of Animal Science. 94:1215–1226.
Moallem zadeh, F., Moghaddam, G. and Soltanpour, F. (2015). Effect of supplemental vitamin C and E on the immune response of newborn calves. Journal of Agri-Food and Applied Science. 3:63-67.
National Research Council. (2001). Nutrient Requirements of Dairy Cattle. 7th Revised Edition, National Academy of Sciences. Washington, D.C.
Prohaska, J.R. and Gybina, A.A. (2004). Intracellular copper transport in mammals. Jornal of Nutrition. 134:1003-1006.
Roy, J.H.B. (1990). The Calf. Vol. 1, Management of health, 5th Edition. Butterworths, London.
Saenko, E.L., Yaropolove, A. and Harris, E.D. (1994). Biological function of ceruloplasmin expressed through Copper- binding sites and a cellular receptor. Journal of Trace Element and Experimental Medicine. 7:69-88.
Spears, J.W., Weiss, W.P. (2008). Role of antioxidants and trace elements in health and immunity of transition dairy cows. Veterinary Journal. 176:70–76.
Sprinkle, J.E., Cuneo, S.P., Frederick, H.M., Enns, R.M., Schafer, D.W., Carstens, G.E. et al. (2006). Effects of a long-acting trace mineral, reticulorumen bolus on range cow productivity and trace mineral profiles. Journal of Animal Science. 84:1439–1453.
Suttle, N.F. (2010). Mineral Nutrition of Livestock. 4th Edition. CABI Publication. Wallingford, UK.
Van Saun, R.J. (2016). Indicators of dairy cow transition risks: Metabolic profiling revisited. Tierarztl Prax Ausg G: Grosstiere Nutztiere. 44:118-126.
Van Soest, P.J., Robertson, J.B and Lewis, B.A. (1991). Methods for dietary fiber, neutral detergent fiber, and non-starch polysaccharides in relation to animal nutrition. Journal of Dairy Science. 74:3593-3597.
Wankhade, P.R., Manimaran, A., Kumaresan, A., Jeyakumar, S., Ramesha, K.P., Sejian, V. et al. (2017). Metabolic and immunological changes in transition dairy cows: A review. Veterinary World. 10:1367-1377.
Weiss, W.P. (2002). Effect of dietary vitamin C on concentrations of ascorbic acid in plasma and milk. Journal of Dairy Science. 84:2302–2307.
Animal Sciences Journal
Volume 33, Issue 127
September 2020
Pages 189-198

Files

Share

How to cite

Statistics