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Impact of Bakery Yeast Cell Wall Beta-Glucan (Saccharomyces cerevisiae) and Bentonite on the Adsorption of Aflatoxin B1 of Mahabadi Dairy Goats

Document Type : Research Paper

Authors

1 PhD student, Department of Animal Sciences, Faculty of Agriculture, University of Birjand.

2 Professor, Department of Animal Sciences, Faculty of Agriculture, University of Birjand.

3 Department of Animal Sciences, Faculty of Agriculture, University of Tehran.

4 Professor, Department of Food Biotechnology, Research Institute of Food Science and Technology (RIFST), Mashhad

Abstract

This study aimed to investigate the reduction of aflatoxinB1 transfer from feed to milk of goats fed a diet contaminated with aflatoxinB1,by pure baker's yeast cell wall beta-glucan(Saccharomyces cerevisiae)in combination with bentonite.Eighteen Mahabadi dairy goats with an initial weight of47.15±4.93 kg were randomly divided into three experimental groups with six replications.The treatments included:1) control (diet containing 25μg/kg dry matter of feed, aflatoxin B1),2)control +3g/day beta-glucan, and 3)control+0.6 g/day beta-glucan+2.4g/day commercial bentonite. After one week of acclimation, all goats underwent a 14-day mild aflatoxin B1 challenge during which dry matter intake, feed efficiency, milk production and composition, the concentration of aflatoxin M1 in the milk, and blood parameters were evaluated. The results showed that the initial and final weight, milk production and composition,dry matter intake and feed efficiency were similar in different groups The concentration of blood urea nitrogen,alanine transaminase,aspartate transaminase, and alkaline phosphatase, concentration,excretion and percentage of aflatoxin M1 transfer in milk changed in different groups compared to the control group (P<0.05). Also, two groups 2and3 showed a significant decrease in the percentage of transfer, concentration and excretion of aflatoxinM1 compared to the positive control group. In general, the results of this study showed that the combination of beta-glucan and bentonite with the ratio specified in this study has the ability to absorb aflatoxinB1 similar to beta-glucan and can reduce the concentration of aflatoxinM1 in milk to the same extent;Therefore,the combination of beta-glucan and bentonite is recommended as a cost-effective adsorbent of aflatoxinB1 compared to pure beta-glucan in livestock diets.

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References
Aazami, M. H., Nasri, M. H. F., Mojtahedi, M., & Mohammadi, S. R. (2018). In vitro aflatoxin B1 binding by the cell wall and (1→ 3)-β-D-glucan of Baker's yeast. Journal of food protection, 81(4), 670-676.
Aazami, M. H., Nasri, M. H. F., Mojtahedi, M., & Battacone, G. (2019). Effect of yeast cell wall and (1→ 3)-β-D-glucan on transfer of aflatoxin from feed to milk in Saanen dairy goats. Animal feed science and technology, 254, 114191.
Abdelhameed, O., & Rabbo, B. A. (2022). A Review on Management Considerations against Mycotoxins in Dairy Cattle Ration. Journal Infect Dis Epidemiol Res, 1(1), 1-6.
Battacone, G., Nudda, A., Cannas, A., Borlino, A. C., Bomboi, G., & Pulina, G. (2003). Excretion of aflatoxin M1 in milk of dairy ewes treated with different doses of aflatoxin B1. Journal of Dairy Science, 86(8), 2667-2675.
Battacone, G., Nudda, A., Palomba, M., Pascale, M., Nicolussi, P., & Pulina, G. (2005). Transfer of aflatoxin B1 from feed to milk and from milk to curd and whey in dairy sheep fed artificially contaminated concentrates. Journal of Dairy Science, 88(9), 3063-3069.
Battacone, G., Nudda, A., Palomba, M., Mazzette, A., & Pulina, G. (2009). The transfer of aflatoxin M1 in milk of ewes fed diet naturally contaminated by aflatoxins and effect of inclusion of dried yeast culture in the diet. Journal of Dairy Science, 92(10), 4997-5004.
Battacone, G., Nudda, A., Rassu, S. P. G., Decandia, M., & Pulina, G. (2012). Excretion pattern of aflatoxin M1 in milk of goats fed a single dose of aflatoxin B1. Journal of dairy science, 95(5), 2656-2661.
Di Gregorio, M. C., Neeff, D. V. D., Jager, A. V., Corassin, C. H., Carão, Á. C. D. P., Albuquerque, R. D., ... & Oliveira, C. A. F. (2014). Mineral adsorbents for prevention of mycotoxins in animal feeds. Toxin Reviews, 33(3), 125-135.
Firmin, S., Morgavi, D. P., Yiannikouris, A., & Boudra, H. (2011). Effectiveness of modified yeast cell wall extracts to reduce aflatoxin B1 absorption in dairy ewes. Journal of dairy science, 94(11), 5611-5619.
Gonçalves, B. L., Gonçalves, J. L., Rosim, R. E., Cappato, L. P., Cruz, A. G. D., Oliveira, C. A. F. D., & Corassin, C. H. (2017). Effects of different sources of Saccharomyces cerevisiae biomass on milk production, composition, and aflatoxin M1 excretion in milk from dairy cows fed aflatoxin B1. Journal of Dairy Science, 100(7), 5701-5708.
Huang, S., Zheng, N., Fan, C., Cheng, M., Wang, S., Jabar, A., ... & Cheng, J. (2017). Effects of aflatoxin B1 combined with ochratoxin A and/or zearalenone on metabolism, immune function, and antioxidant status in lactating dairy goats. Asian-Australasian journal of animal sciences, 31(4), 505.
Institute of Standards and Industrial Research of Iran (ISIRI). (2022). Standard No. 5925: Maximum tolerated level of mycotoxins in food and feed.
Jantaramanant, P., Sermwittayawong, D., Noipha, K., Hutadilok-Towatana, N., & Wititsuwannakul, R. (2014). [Beta]-glucan-containing polysaccharide extract from the grey oyster mushroom [Pleurotus sajor-caju (Fr.) Sing.] stimulates glucose uptake by the L6 myotubes. International Food Research Journal, 21(2), 779.
Jiang, Y., Ogunade, I. M., Kim, D. H., Li, X., Pech-Cervantes, A. A., Arriola, K. G., ... & Adesogan, A. T. (2018). Effect of adding clay with or without a Saccharomyces cerevisiae fermentation product on the health and performance of lactating dairy cows challenged with dietary aflatoxin B1. Journal of dairy science, 101(4), 3008-3020.
Kolosova, A., Stroka, J. 2011. Substances for reduction of the contamination of feed by mycotoxins. A review. World Mycotoxin J. 4, 225-256.
Kong, C., Shin, S.Y., Kim, B.G. 2014. Evaluation of mycotoxin sequestering agents for aflatoxin and deoxynivalenol: an in vitro approach. SpringerPlus, 3,346-351.
Kourousekos, G. D., Theodosiadou, E., Belibasaki, S., Deligiannis, K., Koukoulas, T., Zoulfos, K., & Lymberopoulos, A. G. (2012). Effects of aflatoxin B1 administration on Greek indigenous goats’ milk. International dairy journal, 24(2), 123-129.
Mehany, A. A., & Shams, A. S. E. (2019). Effect of Toxin Binder on Productive Performance of Lactating Friesian Cows. Journal of Animal and Poultry Production, 10(12), 405-413.
Mohaghegh, A., Chamani, M., Shivazad, M., Sadeghi, A. A., & Afzali, N. (2017). Effect of esterified glucomannan on broilers exposed to natural mycotoxin-contaminated diets. Journal of applied animal research, 45(1), 285-291.
Nguyen, T., Flint, S., & Palmer, J. (2020). Control of aflatoxin M1 in milk by novel methods: A review. Food chemistry, 311, 125984.
Omer, N., Khan, J. A., Khan, M. S., Omer, M. O., Avais, M., & Sohail, M. L. (2018). Efficacy of b-glucans and manna oligosaccharides (Yeast Cell Wall) and hydrated sodium calcium aluminosilicate (HSCAS) in preventing aflatoxicosis in bovine calves. Indian journal of animal research, 52(6), 887-892.
Pavlek, Z., Bosnir, J., Kuharic, Z., Racz, A., Jurak, I., Lasic, D., ... & Frece, J. (2022). The influence of binding of selected mycotoxin deactivators and aflatoxin M1 on the content of selected micronutrients in milk. Processes, 10(11), 2431.
Queiroz, O. C. M., Han, J. H., Staples, C. R., & Adesogan, A. T. (2012). Effect of adding a mycotoxin-sequestering agent on milk aflatoxin M1 concentration and the performance and immune response of dairy cattle fed an aflatoxin B1-contaminated diet. Journal of Dairy Science, 95(10), 5901-5908.
Rodrigues, R. O., Ledoux, D. R., Rottinghaus, G. E., Borutova, R., Averkieva, O., & McFadden, T. B. (2019). Feed additives containing sequestrant clay minerals and inactivated yeast reduce aflatoxin excretion in milk of dairy cows. Journal of dairy science, 102(7), 6614-6623.of
Salem, F. A. F., El-Amary, H., & Hassanin, S. H. (2001). Effect of bentonite supplementation on nutrients digestibility; rumen fermentation; some blood physiological parameters and performance of growing lambs. Egyptian Journal of Nutrition and Feeds, 4, 179-191.
 
Santos, R. R., & Fink-Gremmels, J. (2014). Mycotoxin syndrome in dairy cattle: Characterisation and intervention results. World Mycotoxin Journal, 7(3), 357-366.
 
Savari, M., Banadaki, M. D., Rezayazdi, K., & Javan-Nikkhah, M. (2013). A comparison of mineral adsorbents zeolite and Bentonite vs. organic adsorbent (Mycosorb) and mineral-organic adsorbent (Biotox) as their regardstheir potential of adsorbing aflatoxin B1.
Ullah, H. A., Durrani, A. Z., Ijaz, M., Javeed, A., Sadique, U., Hassan, Z. U., ... & Khattak, I. (2016). Dietary mycotoxins binders: A strategy to reduce aflatoxin m1 residues and improve milk quality of lactating Beetal goats. Journal für Verbraucherschutz und Lebensmittelsicherheit, 11, 305-309.
Vila Donat, P., Marín Sillué, S., Sanchís Almenar, V., & Ramos Girona, A. J. (2017). Evaluación de nuevos adsorbentes multimicotoxínicos basados en bentonitas para alimentación animal.
Wang, Q., Zhang, Y., Zheng, N., Guo, L., Song, X., Zhao, S., & Wang, J. (2019). Biological system responses of dairy cows to aflatoxin B1 exposure revealed with metabolomic changes in multiple biofluids. Toxins, 11(2), 77.
Wielogórska, E., MacDonald, S., & Elliott, C. T. (2016). A review of the efficacy of mycotoxin detoxifying agents used in feed in light of changing global environment and legislation. World Mycotoxin Journal, 9(3), 419-434.
Xiong, J. L., Wang, Y. M., Nennich, T. D., Li, Y., & Liu, J. X. (2015). Transfer of dietary aflatoxin B1 to milk aflatoxin M1 and effect of inclusion of adsorbent in the diet of dairy cows. Journal of Dairy Science, 98(4), 2545-2554.
Yiannikouris, A., André, G., Poughon, L., François, J., Dussap, C. G., Jeminet, G., ... & Jouany, J. P. (2006). Chemical and conformational study of the interactions involved in mycotoxin complexation with β-D-glucans. Biomacromolecules, 7(4), 1147-1155
Research Journal of Livestock Science
Volume 39, Issue 151
September 2026
Pages 117-130
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